15
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN2601 | 12-O-Methylcarnosic acid | Reductase | |
12-O-Methylcarnosic acid is a diterpene carnosic acid isolated from Salvia microphylla, is an active constituent of 5α-Reductase inhibition with an IC50 value of 61.7 μM. 12-O-Methylcarnosic acid has Antioxidant activity... | |||
T3378 | Alpha-Estradiol | Alfatradiol,17α-Estradiol,Epiestrol,Epiestradiol | Estrogen/progestogen Receptor , Reductase , Endogenous Metabolite |
Alpha-Estradiol (Epiestradiol) is an estrogen that inhibits 5alpha-reductase and has potential in the study of androgenetic alopecia. | |||
T0488 | Finasteride | MK-906 | Reductase |
Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM. | |||
T1499 | Dutasteride | GG 745,Avodart,GI 198745 | Apoptosis , Reductase |
Dutasteride (GI 198745) is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia. | |||
T71703L | Isomer-Turosteride | Isomer-Turosteride(Isomer-137099-09-3) | Reductase |
Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) is a novel 5 alpha-reductase inhibitor.The antiprostatic effect of Isomer-Turosteride in adult rats is associated with the inhibition of the conversion of T to ... | |||
T28249 | Ono-3805 sodium | Ono3805,Ono 3805,Ono-3805 | |
Ono-3805 is an inhibitor of nonsteroidal 5 alpha-reductase. | |||
T68757 | RMI-18341 | ||
RMI-18341 is a Testosterone 5 alpha reductase inhibitor. | |||
T70343 | FK-143 | ||
FK-143 is a 5-alpha reductase inhibitor. | |||
T70449 | Fce 28260 | ||
Fce 28260 is a 5 alpha-reductase inhibitor. | |||
T70438 | FCE-28175 | ||
FCE-28175 is a 5-alpha reductase inhibitor and hormone antagonist. | |||
T70448 | FCE-27837 | ||
FCE-27837 is a 5-alpha reductase inhibitor and hormone antagonist. | |||
T10179 | 5β-Dutasteride | Others | |
5β-Dutasteride is the S configuration of Dutasteride. It is a potent inhibitor of both 5 alpha-reductase isozymes. | |||
T10780 | CGP-53153 | Others | |
CGP-53153 is a steroidal inhibitor of 5 alpha-reductase (IC50s: 36 and 262 nM in rat and human prostatic tissue). | |||
T19574 | TBHBA | 2,4,6-Tribromo-3-hydroxybenzoic acid | Others |
TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a brominated aromatic compound. It has been found to inhibit the enzyme cyclooxygenase-2 (COX-2), the enzyme lipoxygenase (LOX), the enzyme 5-lipoxygenase (5-LOX), the enzy... | |||
TN5153 | Torilin | MMP , ERK , IκB/IKK , p38 MAPK , NF-κB , Tyrosinase , Reductase , DNA/RNA Synthesis , JNK | |
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than fi... |